BioengineeringbioRxivPreprint
A Micro-Engineered Heart Tissue Model of Desmin-related Cardiomyopathy Caused by Mutant αB Crystalin
Yasaman Kargar Gaz Kooh, Bahareh Bahmani, Chen Zhao…·Nathaniel Huebsch
This paper develops a micro-engineered heart tissue model of desmin-related cardiomyopathy caused by mutant αB crystallin, showing aggregation, contractile dysfunction, and potential therapeutic response to JAK1 inhibition.
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