Siddharth Acharya

Mitochondrial and metabolic plasticity distinguish stem cells from progenitors in the male germline

This study compares mitochondrial and metabolic properties of stem and progenitor cells in the male germline, finding that stem cells exhibit metabolic plasticity and latent oxidative capacity.

Electron tomography reveals mitochondrial network and cristae remodelling during cell differentiation in the human placenta

The paper uses electron tomography to study mitochondrial structure changes during placental cell differentiation, identifying morphological and functional shifts in mitochondria.

The genetic origin of fetal growth restriction and mitochondrial complex I dysregulation

This study identifies SNPs in the nuclear genome associated with fetal growth restriction and mitochondrial complex I dysfunction, impacting placental bioenergetics and birthweight.

Placental Iron Utilisation in Fetal Growth Restriction: Alterations in Mitochondrial Heme Synthesis and Iron-Sulfur Cluster Assembly Pathways

This study investigates iron utilization in placental tissues of fetal growth restriction (FGR) pregnancies, revealing increased iron uptake and prioritization of heme synthesis over iron-sulfur cluster formation.