Alba Caparros-Roissard

The paper investigates sex differences in epigenetic changes linked to chronic pain-induced depression in mice, finding distinct genomic loci but shared regulatory features and gene modules across sexes.

This study identifies sex-specific epigenetic changes in the nucleus accumbens of male and female mice exposed to chronic morphine, revealing shared biological dysregulation and potential therapeutic targets.

This study reviews functional genomic mechanisms of opioid action and OUD across animal models and human studies, finding low consistency in gene expression results.