İpek Yalçın

The paper investigates sex differences in epigenetic changes linked to chronic pain-induced depression in mice, finding distinct genomic loci but shared regulatory features and gene modules across sexes.

The paper examines brain network plasticity during neuropathic pain onset and maintenance in mice, finding stable connectivity during maintenance and changes at onset and post-surgery.

This study shows that repeated restraint stress worsens post-surgical pain and anxiety in rats through β-adrenergic receptor activation and spinal NLRP3-IL1β signaling.

This study identifies sex-specific epigenetic changes in the nucleus accumbens of male and female mice exposed to chronic morphine, revealing shared biological dysregulation and potential therapeutic targets.

The paper investigates brain pH and lactate levels in animal models of neuropsychiatric disorders, finding decreased pH and increased lactate levels as common features across multiple models.

This study identifies the BLA-ACC pathway as critical for chronic pain-induced depression and reveals Sema4a's role in mood regulation through myelination impairments.

The paper studies the time course of homeostatic structural plasticity in mouse anterior cingulate cortex following optogenetic stimulation, showing dynamic changes in neural activity and morphology.

The paper compares structural and functional brain connectivity between C57BL/6 and BALB/cJ mice using MRI techniques, revealing strain-specific differences in brain morphology and connectivity patterns.

The paper investigates how early-life adversity affects epigenetic layers and gene expression in the amygdala, finding associations with immune and small GTPase dysregulation.

The paper shows that increasing spinal acetylcholine levels through low-dose AChE inhibitors reduces mechanical allodynia in neuropathic mice.

This study shows that isoflurane anesthesia produces antidepressant-like effects in rodents by activating TrkB signaling and related molecular pathways.