Nodal is a short-range morphogen with activity that spreads through a relay mechanism in human gastruloids
Lizhong Liu, Anastasiia Nemashkalo, Luisa Rezende, Ji Yoon Jung, Sapna Chhabra, M. Cecilia Guerra, Idse Heemskerk, Aryeh Warmflash
The paper shows Nodal is a short-range morphogen in human gastruloids, spreading via a relay mechanism and regulated by Lefty.
Nature Communications · Jan 25, 2022Peer-reviewedDevelopmental Biology