Juxtaposition of human pluripotent stem cells with amnion-like cells is sufficient to trigger primitive streak formation
Xiangyu Kong, Anastasiia Nemashkalo, M. Cecilia Guerra…·Aryeh Warmflash
This study shows that juxtaposing amnion-like cells with human pluripotent stem cells initiates gastrulation behaviors, including primitive streak formation and mesendodermal differentiation.