Andrey Nikolaev

Structure of a dodecameric double-ferritin-fold protein from an Asgard archaeon

The paper determines the Cryo-EM structure of a dodecameric double-ferritin-fold protein from an Asgard archaeon, revealing its unique structural features and implications for iron metabolism.

CARS: A General Force Field for Carotenoids

The paper introduces CARS, a transferable force field for carotenoids that improves simulation accuracy across diverse chemical structures and outperforms existing force fields.

Structural and Functional Characterization of Encapsulin-Targeted Double Ferritin Fold Ferroxidases

The paper identifies and characterizes double ferritin-like proteins (DFLPs) that form homodimers, bind heme, and exhibit ferroxidase activity, with some targeted to encapsulin shells.

Discovery of excited state proton transfer in flavin-based fluorescent protein with large Stokes shift

The paper discovers a flavin-based fluorescent protein, LSSFbFP, with a large Stokes shift, achieved through excited state proton transfer, and validates its mechanism using spectroscopy and crystallography.

Engineering of soluble bacteriorhodopsin

This paper describes the engineering of soluble bacteriorhodopsin analogues and reports their crystal structure, demonstrating the potential of protein engineering for developing molecular tools.