NeurosciencebioRxivPreprint
Angiotensin Converting Enzyme (ACE) expression in microglia reduces amyloid β deposition and neurodegeneration by increasing SYK signaling and endolysosomal trafficking.
Andrew R. Gomez, Hyae Ran Byun, Shaogen Wu…·Warren G. Tourtellotte
This study shows that ACE expression in microglia reduces amyloid β deposition and neurodegeneration by enhancing SYK signaling and endolysosomal trafficking in Alzheimer's disease models.
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