Author

Hyae Ran Byun

University of California, Los Angeles

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Systems Biology· 3 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Approach:statistical model· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Assay:bulk RNA-seq· 2 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Fernando Gómez‐PinillaiD· 3 shared Guanglin ZhangiD· 3 shared Xia YangiD· 3 shared Zhe YingiD· 3 shared In Sook Ahn· 2 shared AKM Ghulam Muhammad· 1 shared Aldons Jake LusisiD· 1 shared Alek MuroiD· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersSystems Biology

Fernando Gómez‐PinillaORCID

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Author profile →

4 papers

Recent·Most cited

Angiotensin Converting Enzyme (ACE) expression in microglia reduces amyloid β deposition and neurodegeneration by increasing SYK signaling and endolysosomal trafficking.

Andrew R. Gomez, Hyae Ran Byun, Shaogen Wu, AKM Ghulam Muhammad, Jasmine Ikbariyeh, Jaelin Chen, Alek Muro, Lin Li, Kenneth E. Bernstein, Richard I. Ainsworth, Warren G. Tourtellotte

This study shows that ACE expression in microglia reduces amyloid β deposition and neurodegeneration by enhancing SYK signaling and endolysosomal trafficking in Alzheimer's disease models.

bioRxiv · Apr 24, 2024 · PreprintNeuroscience

Host Genetic Background and Gut Microbiota Contribute to Differential Metabolic Responses to High Fructose Consumption in Mice

In Sook Ahn, Jennifer M Lang, C. Anders Olson, Graciel Diamante, Guanglin Zhang, Zhe Ying, Hyae Ran Byun, Ingrid Cely, Jessica Ding, Peter Cohn, Ira Kurtz, Fernando Gómez‐Pinilla, Aldons Jake Lusis, Elaine Y. Hsiao, Xia Yang

This study shows that gut microbiota differences between mouse strains contribute to varied metabolic responses to high fructose consumption, with Akkermansia playing a key protective role.

Journal of Nutrition · Jul 17, 2020Peer-reviewedSystems Biology

Differential Metabolic and Multi-tissue Transcriptomic Responses to Fructose Consumption among Genetically Diverse Mice

Guanglin Zhang, Hyae Ran Byun, Zhe Ying, Montgomery Blencowe, Yuqi Zhao, Jason S. Hong, Le Shu, Karthickeyan Chella Krishnan, Fernando Gómez‐Pinilla, Xia Yang

This study examines how fructose affects metabolic and transcriptomic responses in genetically diverse mice, identifying strain-specific pathways and regulators involved in metabolic dysfunctions.

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · Oct 25, 2019Peer-reviewedSystems Biology

Single Cell Molecular Alterations Reveal Pathogenesis and Targets of Concussive Brain Injury

Douglas V. Arneson, Guanglin Zhang, Zhe Ying, Yumei Zhuang, Hyae Ran Byun, In Sook Ahn, Fernando Gómez‐Pinilla, Xia Yang

This study uses single-cell sequencing to identify hippocampal cell types and genes vulnerable to concussive TBI, revealing pathogenic mechanisms and therapeutic targets.

Nature Communications · Sep 19, 2018Peer-reviewedSystems Biology