Author

Marie Goxe

Idorsia Pharmaceuticals Ltd (Switzerland)ORCID 0009-0004-2871-8660Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Agnes KnopfiD· 1 shared Alexandra HardyiD· 1 shared Alexandre GrimaldiiD· 1 shared Andrew J. PierceiD· 1 shared Anna ThalleriD· 1 shared Carmela Gnerre· 1 shared Caroline HoffmanniD· 1 shared Eva Huehn· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPharmacology & Toxicology

Agnes KnopfORCID

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1 paper

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintFeb 10, 2026

OKN4395, a first-in-class EP2/EP4/DP1 triple antagonist reprograms prostanoid-driven immunosuppression to restore antitumor immunity

Maximilien Grandclaudon, Morgane Boulch, Anna Thaller…·Andrew J. Pierce

OKN4395, a triple EP2/EP4/DP1 antagonist, restores antitumor immunity by reversing prostanoid-driven immunosuppression and synergizes with anti-PD1 therapy.

DOI 10.64898/2026.02.08.704632

experimental assaydrug response / drug discovery

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