This study compares hypothermic and normothermic machine perfusion in a murine kidney model, finding that NMP causes more severe tubular injury and immune cell mobilization compared to HMP.

bioRxiv · Oct 14, 2026 · PreprintImmunology

Sex differences in vaccine induced immunity and protection against Mycobacterium tuberculosis

Gishnu Harikumar Parvathy, David Hertz, Dhananjay Bhandiwad, Lars F. Eggers, Linda von Borstel, Jochen Behrends, Martina Hein, Viola Dreyer, Jaqueline Marschner, Zane Orinska, Stefan Niemann, Stefan H. E. Kaufmann, Torsten Goldmann, Hannelore Lotter, Mario Alberto Flores‐Valdez, Bianca E. Schneider

This study investigates sex differences in immune response to TB vaccines in mice, finding that male mice show poorer BCG vaccine efficacy and specific CD8 T cell deficiencies compared to females.

The Journal of Infectious Diseases · Jun 4, 2025Peer-reviewedImmunology

Ablation of B cell-derived IL-10 increases tuberculosis resistance

D. Hertz, Sebastian Marwitz, Lars F. Eggers, Linda von Borstel, Gishnu Harikumar Parvathy, Jochen Behrends, Danny David Jonigk, Rudolf Armin Manz, Torsten Goldmann, Bianca E. Schneider

This study shows that removing B cell-derived IL-10 increases resistance to tuberculosis in mice, with stronger effects in males.

Frontiers in Immunology · Apr 7, 2025Peer-reviewedImmunology