SERPINB13 is a prognostic biomarker for LUSC associated with an immune-inflamed tumor phenotype and modulated by immune cells
Christiane Kuempers, Karina Stein, Doerte Nitschkowski…·Torsten Goldmann
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Research Center Borstel - Leibniz Lung CenterORCID 0000-0002-1621-560XUnclaimed ORCID profile · follow to get notified of new preprints
8 papers
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Christiane Kuempers, Karina Stein, Doerte Nitschkowski…·Torsten Goldmann
Volker Meidl, Martina Kiefmann, Torsten Goldmann…·Rainer Kiefmann
The paper identifies a hierarchical purinergic receptor activation system in human airway epithelial cells, where P2Y2 regulates P2Y6 and P2Y12 activity.
Christiane Kuempers, Hauke Roettger, Tobias Jagomast…·Torsten Goldmann
Jana Neuber, Florens Lohrmann, Samuel Wald…·Philipp Henneke
The paper investigates KC plasticity in mycobacterial infections, finding that KClow cells derived from bona fide KCs exhibit unique antimycobacterial activity and adaptability.
Ayse Seda Yazgili, Georgia A. Giotopoulou, Sabine J. Behrend…·Silke Meiners
This study shows PA200 regulates proteasome composition and inhibits cancer cell migration, with cell-specific effects on integrin and ECM regulators.
Gishnu Harikumar Parvathy, David Hertz, Dhananjay Bhandiwad…·Bianca E. Schneider
This study investigates sex differences in immune response to TB vaccines in mice, finding that male mice show poorer BCG vaccine efficacy and specific CD8 T cell deficiencies compared to females.
D. Hertz, Sebastian Marwitz, Lars F. Eggers…·Bianca E. Schneider
This study shows that removing B cell-derived IL-10 increases resistance to tuberculosis in mice, with stronger effects in males.
D. Hertz, Lars F. Eggers, Linda von Borstel…·Bianca E. Schneider
This study shows that in the absence of adaptive immunity, female mice are more susceptible to Mtb than males, highlighting a sex-based difference in innate immune responses.