Molecular BiologyNature CommunicationsPeer-reviewed
Structural basis for selective inhibition of human GABA transporter GAT3
Jonas Sigurd Mortensen, Francesco Bavo, Malene Hall Jensen…·Azadeh Shahsavar
This study presents cryo-EM structures of human GAT3 bound to inhibitor, substrate GABA, or in substrate-free state, revealing molecular mechanisms of inhibition and substrate recognition.
3 citations