Author

Akiko Hayashi‐Takagi

Gunma UniversityORCID 0000-0001-7216-6972Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:statistical model· 3 Research Focus:benchmarking· 2 Organism:human· 2 Organism:mouse· 2 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Assay:metabolomics· 1

Frequent Co-Authors

Kisho Obi-NagataiD· 2 shared Akiko Watanabe· 1 shared Akinobu MatsumotoiD· 1 shared Akio KiharaiD· 1 shared Akito NakaoiD· 1 shared Akiyoshi KakitaiD· 1 shared Anja UrbachiD· 1 shared Atsuko Hayata‐TakanoiD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersNeuroscience

Kisho Obi-NagataORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Human-specific fast synaptic kinetics enable rapid detection of predictive features

Kisho Obi-Nagata, Norimitsu Suzuki, Kenzo Kosugi, Katsuya Ozawa, Hiroki Sasaguri, Kimie Niimi, Kentaro Miyamoto, Masaki Takao, Masahiro Toda, Toshitake Asabuki, Akiko Hayashi‐Takagi

The paper compares synaptic kinetics across mammals and finds human neurons have faster excitatory transmission, leading to better pattern detection in noise during unsupervised learning.

bioRxiv · Nov 3, 2025 · PreprintNeuroscience

Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment

Hideo Hagihara, Hirotaka Shoji, Satoko Hattori, Giovanni Sala, Yoshihiro Takamiya, Mika Tanaka, Masafumi Ihara, Mihiro Shibutani, Izuho Hatada, Kei Hori, Mikio Hoshino, Akito Nakao, Yasuo Mori, Shigeo Okabe, Masayuki Matsushita, , Michihiro Igarashi

The paper investigates brain pH and lactate levels in animal models of neuropsychiatric disorders, finding decreased pH and increased lactate levels as common features across multiple models.

eLife · Sep 1, 2023Peer-reviewedNeuroscience

Investigation of betaine as a novel psychotherapeutic for schizophrenia

Tetsuo Ohnishi, Shabeesh Balan, Manabu Toyoshima, Motoko Maekawa, Hisako Ohba, Akiko Watanabe, Yoshimi Iwayama, Yūkō Fujita, Yunfei Tan, Yasuko Hisano, Chie Shimamoto‐Mitsuyama, Yayoi Nozaki, Kayoko Esaki, Atsuko Nagaoka, Junya Matsumoto, , Takeo Yoshikawa

This study investigates betaine's role in schizophrenia using metabolomics and genetic approaches, finding it may alleviate oxidative stress and improve cognitive function in specific cases.

EBioMedicine · Jun 26, 2019Peer-reviewedNeuroscience