Author
Children's Medical CenterORCID 0009-0004-4497-7080Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Kalil G. Abdullah, Kenji Miki, Charles K. Edgar…·Samuel K. McBrayer
This study identifies GAA accumulation in gliomas as a driver of neuronal activity and tumor growth, linking cancer metabolism to neuroscience through GABAA receptor activation.
Alex C. Sternisha, Haocheng Li, Kumar Gajendra…·Samuel K. McBrayer
The paper develops a biosensor to monitor α-ketoglutarate in human cells and identifies a mitochondrial-to-nuclear pathway regulating chromatin methylation.
Milan R. Savani, Bingbing Li, Bailey C. Smith…·Samuel K. McBrayer
The paper develops a platform to trace 30 nitrogen isotope-labeled metabolites, revealing cell state-specific pyrimidine synthesis pathway preferences in primitive and differentiated cells.
Yi Xiao, Diana D. Shi, Lei Guo…·Samuel K. McBrayer
This study shows mutant IDH reprograms neural progenitor cell fate by silencing Gsx2, promoting gliomagenesis through lineage switching.