Author

Nandakumar Rajasekaran

Johns Hopkins UniversityORCID 0009-0004-4624-0824Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Assay:fluorescence / live-cell microscopy· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Christian KaiseriD· 2 shared Brett O’Brien· 1 shared Dmitri D. ToptyginiD· 1 shared Gabriel Jiménez-AvalosiD· 1 shared Roumita MoulickiD· 1 shared Sarah A. WoodsoniD· 1 shared Taekjip HaiD· 1 shared Ting‐Wei LiaoiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 20 mutual co-author links

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2 shared papersBiophysics

Christian KaiserORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintMar 10, 2026

Multivalent weak contacts shape chaperone-nascent protein interactions

Nandakumar Rajasekaran, Dmitri D. Toptygin, Ting‐Wei Liao…·Christian Kaiser

This study uses single-molecule techniques to show that trigger factor interacts with nascent proteins via multiple weak, dynamic contacts that evolve during elongation.

1 citation

bacteria (other)fluorescence / live-cell microscopy

𝕏 PostBluesky

BiophysicsNature CommunicationsPeer-reviewedOct 9, 2024

Stick-slip unfolding favors self-association of expanded HTT mRNA

Brett O’Brien, Roumita Moulick, Gabriel Jiménez-Avalos…·Sarah A. Woodson

The paper investigates the folding behavior of expanded HTT mRNA and finds that stick-slip dynamics contribute to its aggregation propensity.

4 citations

experimental assay

𝕏 PostBluesky