Synthetic BiologyMetabolic EngineeringPeer-reviewed
Biosensor-guided evolution of chalcone synthase enhances biosynthesis of natural and non-natural flavanones
Erik K. R. Hanko, Chatchai Kesornpun, Joshua N. Whitehead…·Nigel Shaun Scrutton
The paper improves microbial production of diverse flavanones by evolving chalcone synthases using a biosensor-based screening approach.
DOI 10.1016/j.ymben.2026.102564