NeurosciencebioRxivPreprint
Resting state fMRI detects pathological functional brain connectivity in the Ndufs4 knockout mouse model of Leigh syndrome during the pre-symptomatic stage of the disease
Chao Ciu-Gwok Guo, Melissa van de Wal, Samir el Bouazzati…·Judith Regina Homberg
The paper uses rs-fMRI to detect altered functional connectivity in Ndufs4 knockout mice during the pre-symptomatic stage of Leigh syndrome, finding increased connectivity in multiple brain regions and no effect of KH176 treatment.