The paper identifies a symbiont-derived biosurfactant that links host neuroimmune control of intestinal peristalsis with bacterial susceptibility to expulsion.

bioRxiv · Sep 28, 2026 · PreprintMicrobiology

Evolutionary trade-offs between antimicrobial resistance and virulence in Pseudomonas aeruginosa

Surajit Pal, Anton Mohn, Michael Habig, Barbara Pees, Hinrich Schulenburg Y

This study investigates how resistance to different antibiotics affects virulence in Pseudomonas aeruginosa, finding antibiotic-specific trade-offs between resistance and virulence.

bioRxiv · Jul 10, 2026 · PreprintEvolutionary Biology

Polyketide synthase-derived sphingolipids determine microbiota-mediated protection against pathogens in C. elegans

Lena Peters, Moritz Drechsler, Michael A. Herrera, Jing Liu, Barbara Pees, Johanna Jarstorff, Anna Czerwinski, Francesca Lubbock, Georgia Angelidou, Liesa Salzer, Karlis Arturs Moors, Nicole Paczia, Yi‐Ming Shi, Hinrich Schulenburg Y, Christoph Kaleta, , Katja Dierking

The paper identifies sphingolipids from a bacterial PKS as mediators of microbiota protection against pathogens in C. elegans.

Nature Communications · Jun 3, 2025Peer-reviewedMolecular Biology

The C. elegans proteome response to two protective Pseudomonas symbionts

Barbara Pees, Lena Peters, Christian Treitz, Inga K. Hamerich, Kohar Annie B. Kissoyan, Andreas Tholey, Katja Dierking

This study uses proteomics to compare C. elegans responses to two protective Pseudomonas symbionts, identifying distinct host pathways involved in pathogen resistance and tolerance.

mBio · Feb 27, 2024Peer-reviewedMolecular Biology