Author
Henry M. Jackson FoundationORCID 0009-0004-5105-4583Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Beatriz German, Kun-Lin Ho, Jennifer M. Garbarino…·Leigh Ellis
The paper identifies population-associated differences in chromatin regulation in prostate cancer, linking reduced CTCF accessibility to aggressive tumor biology in Black men.
Beatriz German, Katherine L. Morel, Teia Noel…·Leigh Ellis
This paper identifies the EZH2-TTP-mTORC1 axis as a driver of phenotypic plasticity and therapeutic vulnerability in prostate cancer, showing that combined inhibition of EZH2 and PI3K/mTORC1 improves anti-tumor activity.
Beatriz German, Jagpreet N. Singh, Marcos AdS Fonseca…·Leigh Ellis
This study identifies MYBL2 as a master regulator of phenotypic plasticity in prostate cancer and shows CDK2 inhibition as a potential therapeutic strategy for MYBL2-driven tumors.