Author

Katherine L. Morel

The University of AdelaideORCID 0000-0002-7968-4032Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Ayesha A. ShafiiD· 1 shared Beatriz GermaniD· 1 shared Christopher J. SweeneyiD· 1 shared David P. LabbéiD· 1 shared Deborah L. BurkhartiD· 1 shared Felipe Segato DezemiD· 1 shared Henry W. LongiD· 1 shared Himisha BeltraniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Ayesha A. ShafiORCID

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1 paper

Recent·Most cited

EZH2-TTP-mTORC1 Axis Drives Phenotypic Plasticity and Therapeutic Vulnerability in Lethal Prostate Cancer

Beatriz German, Katherine L. Morel, Teia Noel, Nadia Boufaied, Deborah L. Burkhart, Sujun Chen, Felipe Segato Dezem, Xintao Qiu, Henry W. Long, Stefan DiFazio, Sylvan C. Baca, Ayesha A. Shafi, Matthew L. Freedman, Himisha Beltran, Christopher J. Sweeney, , Leigh Ellis

This paper identifies the EZH2-TTP-mTORC1 axis as a driver of phenotypic plasticity and therapeutic vulnerability in prostate cancer, showing that combined inhibition of EZH2 and PI3K/mTORC1 improves anti-tumor activity.

bioRxiv · Aug 7, 2025 · PreprintCancer Biology