Abulimiti Aikedan

This study shows that TDP-43 mutations in ALS/FTD reduce HSV-1 infection by disrupting cell-adhesion pathways and impairing viral entry.

The paper develops a humanized neuroimmune model to study tauopathy and identifies microglial and lncRNA mechanisms that protect neurons.

This study identifies cGAS as a key mediator of TDP-43 pathology in ALS and shows that its inhibition reduces RNA splicing defects and neurodegeneration.