Author

Stephanie Jackvony

Weill Cornell MedicineORCID 0000-0002-9145-7780Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

Adam L. OrriD· 2 shared Anna G. OrriD· 2 shared Constance Q. ZhouiD· 2 shared Abulimiti AikedaniD· 1 shared Avital Licht-MuravaiD· 1 shared Deepak ShuklaiD· 1 shared Evelyn J. HardiniD· 1 shared Fernando PalaguachiiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersNeuroscience

Adam L. OrrORCID

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2 papers

Recent·Most cited

ALS/FTD-linked TDP-43 alterations prevent HSV-1 infection by disrupting cell-adhesion pathways

Stephanie Jackvony, Laraib Ijaz, Evelyn J. Hardin, Abulimiti Aikedan, Constance Q. Zhou, Tejabhiram Yadavalli, Minwoo Wendy Jang, Matthew Mahoney, Li Gan, Deepak Shukla, Adam L. Orr, Anna G. Orr

This study shows that TDP-43 mutations in ALS/FTD reduce HSV-1 infection by disrupting cell-adhesion pathways and impairing viral entry.

bioRxiv · Oct 2, 2026 · PreprintNeuroscience

Astrocytic TDP-43 dysregulation impairs memory by modulating antiviral pathways and interferon-inducible chemokines

Avital Licht-Murava, Samantha M. Meadows, Fernando Palaguachi, Soomin C. Song, Yaron Bram, Constance Q. Zhou, Stephanie Jackvony, Robert E. Schwartz, Robert C. Froemke, Adam L. Orr, Anna G. Orr

This study shows that TDP-43 accumulation in astrocytes impairs memory by altering antiviral pathways and chemokine signaling between astrocytes and neurons.

Science Advances · Apr 19, 2023Peer-reviewedNeuroscience