NeurosciencebioRxivPreprint
Pyruvate kinase activates SARM1 to exacerbate axonal degeneration in diabetic peripheral neuropathy
Jingxuan Liu, Wenxi Li, Chenyu Li…·Wei Yu
This study identifies PKM as a metabolic activator of SARM1 in diabetic neuropathy, showing that inhibiting their interaction reduces axonal degeneration.
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