Developmental BiologybioRxivPreprint
Cullin3 promotes stem cell progeny differentiation by facilitating aPKC-directed asymmetric Numb localization
Hideyuki Komori, Noemí Rives-Quinto, Xu Han…·Cheng‐Yu Lee
This study shows that Cullin3 enhances aPKC activity to localize Numb at the basal cortex, promoting differentiation of Drosophila neural stem cell progeny by downregulating Notch signaling.
DOI 10.1101/2020.07.29.227603