James B. Skeath

This study shows that loss of dihydroceramide desaturase in glial cells causes neurodegeneration by disrupting ER and lipid droplet homeostasis, leading to neuronal death and developmental defects.

The paper presents a split-GAL4 driver library for targeting neuronal lineages in Drosophila VNC, enabling analysis of morphology, neurochemistry, and behavior.

This study identifies genes regulating CNS morphology in Drosophila through a genetic screen, revealing a role for senseless-2 in surface glia.

This paper reports a genetic screen in Drosophila to identify regulators of muscle morphogenesis, finding new loci and alleles associated with muscle development.

This study shows that Cullin3 enhances aPKC activity to localize Numb at the basal cortex, promoting differentiation of Drosophila neural stem cell progeny by downregulating Notch signaling.

This study identifies the role of Unc-4 in promoting neuronal identity and development of the take-off circuit in the Drosophila CNS.

The paper identifies GABA-A rho signaling as essential for maintaining quiescence of melanocyte stem cells in larval zebrafish and preventing excessive pigmentation.