ImmunologybioRxivPreprint
Fructose utilization by GM-CSF-differentiated macrophages aggravates autoimmune inflammation via MG-derived AGE-RAGE signaling
Yeon Jun Kang, Sihyun Chae, Jaemoon Koh…·Won-Woo Lee
This study shows fructose metabolism in GM-CSF-differentiated macrophages promotes autoimmune inflammation through MG-AGE-RAGE signaling by enhancing glycolysis and Th17 differentiation.
DOI 10.64898/2026.01.26.701899