Cell BiologybioRxivPreprint
Lipid Droplet Remodeling Safeguards Redox Balance through the DGAT1-PANK2-NRF2 Axis in Mammalian Oocytes and Drives Age-Associated Decline
Pravin Birajdar, Akshay Kumar, Anjali Kumari…·H. B. D. Prasada Rao
This study identifies the DGAT1-PANK2-NRF2 axis as critical for lipid droplet remodeling, redox balance, and oocyte quality, with dysfunction linked to age-related decline.
DOI 10.1101/2025.11.28.691261