Author

Donald Vardaman

University of Alabama at BirminghamORCID 0009-0004-7999-9458Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Assay:flow cytometry· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Daniel J. TyrrelliD· 3 shared Md Akkas AliiD· 3 shared Harrison Tidwell· 2 shared Mallikarjun N. PatiliD· 2 shared Md. Hasanul Banna SiamiD· 2 shared Ashleigh D. Whatley· 1 shared Ashley S. HarmsiD· 1 shared Chase Bolding· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersImmunology

Daniel J. TyrrellORCID

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintDec 13, 2025

High-Dimensional Single-Cell Analysis Reveals Coordinated Age-Dependent Neuroinflammatory Microglia-T cell Circuits in the Brain

Md Akkas Ali, Md Hasanul Banna Siam, Donald Vardaman…·Daniel J. Tyrrell

This study identifies age-related neuroinflammatory microglia-T cell circuits in a mouse model of vascular dementia using multi-modal high-dimensional analysis.

2 citations

mouseflow cytometry

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Systems BiologyBioinformaticsPeer-reviewedApr 17, 2025

CAFE: An Integrated Web App for High-Dimensional Analysis and Visualization in Spectral Flow Cytometry

Md. Hasanul Banna Siam, Md Akkas Ali, Donald Vardaman…·Daniel J. Tyrrell

CAFE is a web app for analyzing and visualizing high-dimensional spectral flow cytometry data, enabling interactive exploration without coding expertise.

1 citation

humanmultiome

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ImmunologyThe Journal of ImmunologyPeer-reviewedOct 25, 2024

Development of a Spectral Flow Cytometry Analysis Pipeline for High-Dimensional Immune Cell Characterization

Donald Vardaman, Md Akkas Ali, Md. Hasanul Banna Siam…·Daniel J. Tyrrell

The paper develops a spectral flow cytometry analysis pipeline to identify age-related differences in T cell subsets using high-dimensional data from young and aged mice.

13 citations

mouseflow cytometry

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