Cellular modifiers of TDP-43 phase transition and cytoplasmic aggregation
N.Y. Chin, Qi Zhang, Jizhong Zou, Ken Chih-Chien Cheng, Wei Zheng, Yihong Ye
This study identifies cellular factors that modulate TDP-43 phase behavior and shows that nuclear export inhibition reduces its aggregation in a brain organoid model.
eLife · Aug 26, 2026Peer-reviewedCell Biology