Madison E. Jewell

Paradoxical increases in anterior cingulate cortex activity during nitrous oxide-induced analgesia reveal a signature of pain affect

The paper shows that nitrous oxide increases anterior cingulate cortex activity in mice, suggesting this activity reflects pain affect even under anesthesia.

Tetracycline transactivator overexpression in keratinocytes triggers a TRPV1 primary sensory neuron-dependent neuropathic itch

The paper shows that overexpression of tetracycline transactivator in keratinocytes causes neuropathic itch in mice, which can be reversed by inhibiting Gi signaling or ablating TRPV1 neurons.