Michelle D. Jung

The paper measures protein stability for 1.8 million domains using a new experimental method and develops models that accurately predict stability with high precision.

The paper measures conformational fluctuations of protein domains using hydrogen-deuterium exchange mass spectrometry and uses computational modeling to design mutations that stabilize low-stability segments.

The paper quantifies aggregation in small protein domains under stress and uses machine learning to identify predictors, improving aggregation prediction models.