Author

Ruiwen Xu

ORCID 0009-0004-9243-7644Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Hua CheniD· 1 shared Hui Bao· 1 shared Juan Li· 1 shared Kai LviD· 1 shared Lu Han· 1 shared Na LiiD· 1 shared Qiang LiiD· 1 shared Rui Qi· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioengineering

Hua ChenORCID

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1 paper

Recent·Most cited

Segmented poly(A) tails with microRNA target sites confer tissue-specific regulation for mRNA therapeutics

Rui Qi, Hua Chen, Hui Bao, Ying Sun, Ruiwen Xu, Lu Han, Yingmei Xu, Juan Li, Na Li, Qiang Li, Tingting Zhang, Kai Lv, Yijie Dong, Shan Cen, Weiguo Zhang

This study engineers segmented poly(A) tails with microRNA target sites to enable tissue-specific regulation of mRNA-LNPs, showing position-dependent expression control in vitro and in vivo.

Molecular Therapy — Nucleic Acids · Sep 8, 2026Peer-reviewedBioengineering