Developmental BiologybioRxivPreprint
SWI/SNF-Dependent Chromatin Remodelling Establishes Gene Regulatory Programs in Early Human Embryos and Blastoids
Sam Samuel Franciscus Allegonda van Knippenberg, Maria Tryfonos, Joke De Busscher…·Vincent Pasque
This study shows that SWI/SNF chromatin remodellers are critical for lineage specification in human embryos and blastoids by regulating enhancer accessibility and transcription factor binding.