Tsz-Ki Kwan

In-silico cell sorting revealed granulocyte-specific single-cell-type gene expression from peripheral blood bulk expression data and its application as host response biomarkers to discriminate bacterial and viral infections

The paper develops an in-silico cell sorting method to identify granulocyte-specific gene expression biomarkers from bulk blood data, enabling discrimination between bacterial and viral infections.

A map of Non-translated RNA (nt-RNA) junctions in cancer genomes: a database resource of unproductive splicing

This paper identifies and characterizes toxic junctions from non-translated RNA in cancer genomes, revealing their abundance and potential as biomarkers.

Monocyte single cell-type gene expression measured in peripheral blood by DIRECT LS-TA method: the ratio-based biomarkers of (IFI27/PSAP) showed superior performance than interferon score in triage patients with viral infection

This paper develops a ratio-based biomarker (DIRECT LS-TA) using monocyte-specific gene expression ratios in peripheral blood to improve viral infection triage, outperforming the IFN score in diagnostic accuracy.