Dan Yang Huang

This paper develops a ratio-based biomarker (DIRECT LS-TA) using monocyte-specific gene expression ratios in peripheral blood to improve viral infection triage, outperforming the IFN score in diagnostic accuracy.

This study identifies PARP7 as a key regulator of C/EBPβ-dependent adipogenesis and shows it senses nuclear NAD+ levels to control gene expression and lipid production in mammary glands.

The paper develops a ratio-based biomarker (DIRECT LS-TA) to quantify monocyte-specific gene expression directly from whole blood without cell sorting, showing potential for bacterial infection diagnosis.