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Yifan Chen

Huazhong University of Science and TechnologyORCID 0009-0004-9858-6077Unclaimed ORCID profile · follow to get notified of new preprints

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Yifan Chen1 paper · Hebei Medical University

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Approach:experimental assay· 1

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Bin ZhuiD· 1 shared Bingbing Yu· 1 shared Xueling LuiD· 1 shared Yan YaniD· 1 shared

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Bin ZhuORCID

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1 paper

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Molecular BiologyNucleic Acids ResearchPeer-reviewedJul 9, 2024

DNA-terminus-dependent transcription by T7 RNA polymerase and its C-helix mutants

Bingbing Yu, Yifan Chen, Yan Yan…·Bin Zhu

This study identifies DNA-terminus-initiated transcription by T7 RNA polymerase as the main source of dsRNA byproducts and shows that a C-helix mutant reduces dsRNA production and improves mRNA quality.

17 citations

experimental assay

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