Xueling Lu

The paper identifies a novel 6mA-binding protein from Vibrio cholerae that recognizes the G6mAG motif, differing from DpnI's G6mATC specificity.

This study identifies DNA-terminus-initiated transcription by T7 RNA polymerase as the main source of dsRNA byproducts and shows that a C-helix mutant reduces dsRNA production and improves mRNA quality.

This study uses longitudinal meta-regression to examine how DNA methylation effects on child health outcomes vary by timing, finding larger effects in childhood but noisier associations and time-specific signals.

This paper characterizes a psychrophilic phage RNA polymerase that improves RNA purity and stability in vitro transcription by reducing dsRNA by-products and RNA degradation.