ImmunologyThe Journal of ImmunologyPeer-reviewed
Spleen Tyrosine Kinase (SYK) negatively regulates ITAM-mediated human NK cell signaling and CD19-CAR NK cell efficacy
Alberto Jovani Millan, Vincent Allain, Indrani Nayak…·Lewis L. Lanier
This study shows that SYK negatively regulates NK cell signaling and that its deletion enhances CD19-CAR NK cell efficacy in cancer immunotherapy.
13 citations