Indrani Nayak

The paper uses nonlinear mixed-effects modeling to study synergy between immune checkpoint and thrombin inhibitors in a mouse colon cancer model, identifying mechanisms like CD8+ T cell expansion.

The paper develops a multiscale computational model to predict CD33 CAR-NK cytotoxicity against various target cells using experimental data and flow cytometry.

This study shows that SYK negatively regulates NK cell signaling and that its deletion enhances CD19-CAR NK cell efficacy in cancer immunotherapy.

This study shows that NK cell receptor signaling and activation vary with cell cycle stages, with some proteins showing non-monotonic abundance changes.