Marcos Galán-Ganga

This study identifies sex-dependent interferon signaling as a driver of female-biased Alzheimer's disease vulnerability, showing that targeting this pathway can reduce pathology and improve cognition in female mice.

The paper shows that reduced IKZF1 and IKZF2 in immune cells of schizophrenic patients leads to impaired neural circuits and schizophrenia-like symptoms in mice and human cell models.