NeurosciencebioRxivPreprint
Bone regulates locomotion by sustaining motoneuronal mitochondrial function
David Romeo-Guitart, Tala Tirani, Dimitrije Milunov…·Franck Oury
This study shows that bone-derived hormone osteocalcin regulates locomotion by maintaining mitochondrial function in spinal motoneurons, and that this effect can be reversed in aged mice.
DOI 10.64898/2026.10.07.750453