Author

Jinzhao He

Harvard UniversityORCID 0009-0005-3492-496XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Asma Tchakal-MesbahiiD· 1 shared Dennis BrowniD· 1 shared Hua A. Jenny LuiD· 1 shared Jing Guan· 1 shared Kazuhiko FukushimaiD· 1 shared Ming HuangiD· 1 shared Richard BouleyiD· 1 shared Shuai ZhuiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

Asma Tchakal-MesbahiORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintJun 28, 2026

GR-SAFS: A Graph-Regularized Stacking Framework with Adaptive Feature Selection for High-Dimensional Prognostic Biomarker Discovery

Jinzhao He, Jing Guan

GR-SAFS identifies a 20-gene prognostic signature from TCGA-LUAD data with high concordance index, outperforming other methods in external validation.

DOI 10.64898/2026.06.23.733986

humanbulk RNA-seq

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Cell BiologyAmerican Journal of Physiology-Renal PhysiologyPeer-reviewedAug 26, 2025

Focal Adhesion Kinase (FAK) inhibition induces membrane accumulation of aquaporin2 (AQP2) through endocytosis inhibition and actin depolymerization in renal epithelial cells.

Asma Tchakal-Mesbahi, Jinzhao He, Shuai Zhu…·Hua A. Jenny Lu

This study shows FAK inhibition leads to AQP2 membrane accumulation by blocking endocytosis and causing actin depolymerization in renal cells.

3 citations

proteomicsexperimental assay

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