Bottom-up proteomics under acidic conditions using protease type XIII from Aspergillus saitoi
Ryota Tomioka, Ayana Tomioka, Kosuke Ogata, Yasushi Ishihama
This study demonstrates that protease type XIII from Aspergillus saitoi improves bottom-up proteomics under acidic conditions by enhancing sequence coverage and reducing modification artifacts compared to trypsin.