Luis Miguel Cerron-Alvan

The paper identifies Wt1 splice isoforms as regulators of lineage-associated transcriptional programs during formative pluripotency, showing that alternative splicing tunes lineage bias.

This study reveals that PHLPP2 is a pseudophosphatase with no catalytic activity, challenges its role as a tumor suppressor, and identifies its non-catalytic functions in Akt signaling.

This study identifies FoxO transcription factors as essential for transitioning from naive to formative pluripotency by regulating enhancer activity through AKT signaling.