Author

Hao-Cheng Gao

Purdue University West LafayetteORCID 0009-0005-4026-0127Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:imaging· 2 Organism:mouse· 2 Approach:Bayesian inference· 1 Research Focus:cell type annotation· 1 Research Focus:dimensionality reduction· 1 Assay:electronic health records· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Fan XuiD· 3 shared Alexander A. ChubykiniD· 2 shared Fang HuangiD· 2 shared Tailong CheniD· 2 shared Yiwen LiiD· 2 shared Adam KimbroughiD· 1 shared Cheng BiiD· 1 shared Christopher J. Quinn· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersNeuroscience

Fan XuORCID

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3 papers

Recent·Most cited

BiophysicsbioRxivPreprintOct 28, 2026

Bayesian in situ point spread function modeling enables high-fidelity three-dimensional nanoscopy in deep tissue

Jian Cao, Yiwen Li, Yuyuan Qiao…·Fan Xu

This paper introduces Bayesian in situ PSF modeling to improve 3D nanoscopy in deep tissue by accounting for optical distortions and uncertainties in PSF estimation.

DOI 10.64898/2026.10.27.761841

imagingBayesian inference

𝕏 PostBluesky

NeuroscienceNature CommunicationsPeer-reviewedApr 22, 2026

Interferometric Ultra-High Resolution 3D Imaging through Brain Sections

Hao-Cheng Gao, Fan Xu, Xi Cheng…·Fang Huang

This paper introduces 4Pi-BRAINSPOT, a method for ultra-high-resolution 3D imaging of molecular structures in brain tissue with sub-15-nm resolution.

1 citation

mouseimaging

𝕏 PostBluesky

NeurosciencebioRxivPreprintJul 23, 2024

Impaired experience-dependent inter-areal network connectivity across the visual cortex in Fmr1 KO mice

Xi Cheng, Sanghamitra Nareddula, Hao-Cheng Gao…·Alexander A. Chubykin

This study examines how visual experience affects inter-areal network connectivity in the visual cortex of Fmr1 KO mice, revealing impaired synchronization and synaptic connectivity in FX models.

1 citation

mouseelectronic health records

𝕏 PostBluesky