Author

Jian Cao

Rutgers, The State University of New Jersey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1 Cell Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Approach:Bayesian inference· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Wenjin Chen· 2 shared Adam RobinsoniD· 1 shared Alexander KleyiD· 1 shared Amartya SinghiD· 1 shared Arthur Roberts· 1 shared Baoli ZhuiD· 1 shared Christian S. HinrichsiD· 1 shared Christopher Alcott· 1 shared

Activity by Year

2020-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCancer Biology

Wenjin Chen

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Bayesian in situ point spread function modeling enables high-fidelity three-dimensional nanoscopy in deep tissue

Jian Cao, Yiwen Li, Yuyuan Qiao, Tailong Chen, Yiqing Zhang, Hao-Cheng Gao, Junyi Zhang, Lirong Qiu, Jianli Liu, Fan Xu

This paper introduces Bayesian in situ PSF modeling to improve 3D nanoscopy in deep tissue by accounting for optical distortions and uncertainties in PSF estimation.

bioRxiv · Oct 28, 2026 · PreprintBiophysics

BLTP3A dysfunction unleashes lysosomal stress-induced antitumor immunity through STING

Elaheh Sadat Hosseini, Steven Wang, Mona Arabzadeh, Kristen E. Warrington, Maria T. Søgaard, Amartya Singh, Wenjin Chen, Lomaani Ranasinghe, Rinkee Kumari, Christopher Alcott, Adam Robinson, Shreya Yadav, Wenwei Hu, Jian Cao, Eugenia Girda, , Kyle Kristopher Payne

This study shows that BLTP3A dysfunction leads to lysosomal stress, which activates STING and promotes antitumor immunity by sustaining IFN-λ production in ovarian cancer.

bioRxiv · Sep 28, 2026 · PreprintCancer Biology

Hypoxia-induced metastatic heterogeneity in pancreatic cancer

Pradeep Moon Gunasekaran, Qianqian Wang, Polina Guseva, Yoke‐Chen Chang, Rajika Chauhan, Alexander Kley, Mengdie Xu, Gene Lee, Gregory Marshall, Siddharth Ghosh Roy, Yousef Masoudpoor, Oscar Li, Arthur Roberts, Kelly Watkins Walton, Lucyann Franciosa, , Shin‐Heng Chiou

This study shows hypoxia promotes metastasis in pancreatic cancer by suppressing Kdm8, leading to epigenetic and transcriptomic changes, increased chromosomal instability, and metastatic disease.

Nature Communications · Jul 30, 2026Peer-reviewedCell Biology

Body site-specific and disease-specific virulome in the human microbiome

Fei Liu, Wanting Dong, Yaqiong Guo, Qian Xiong, Na Lü, Xiaofeng Song, Yong Xue, Demin Cao, X. Fan, Fang Yuan, Zhiyuan Li, Jian Cao, Yanan Wang, Guowei Yang, George F. Gao, , Baoli Zhu

The paper analyzes the virulome across different body sites and diseases, finding higher VF diversity in the oral cavity and disease-specific VF abundance.

bioRxiv · Dec 13, 2020 · PreprintGenomics