Author

Emma Wagner

Stanford MedicineORCID 0009-0005-4095-0945Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell-cell communication· 3 Organism:human· 3 Assay:spatial transcriptomics· 3 Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Research Focus:spatial domain detection· 2

Frequent Co-Authors

Amanda KiraneiD· 4 shared Banafshé LarijaniiD· 3 shared Christopher J. ApplebeeiD· 3 shared Julian A. PadgetiD· 3 shared Jay ChadokiyaiD· 2 shared Mamatha SerasanambatiiD· 2 shared Prabhjeet SinghiD· 2 shared Saurabh SharmaiD· 2 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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Curved chords = mutual co-authorship

4 shared papersCancer Biology

Amanda KiraneORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

ImmunologybioRxivPreprintSep 29, 2026

Patient-Derived Melanoma Organoids Preserve Tumor-Immune Heterogeneity and Reveal Context-Dependent Responses to Immune Checkpoint Blockade

Mamatha Serasanambati, Jay Chadokiya, Michitaka Nakano…·Amanda Kirane

This study establishes patient-derived melanoma organoids (PDMOs) that retain tumor-immune heterogeneity and show context-dependent responses to immune checkpoint blockade.

DOI 10.64898/2026.09.23.753873

humanexperimental assay

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Cancer BiologybioRxivPreprintMay 21, 2026

Integrated Spatial Multi-omic Profiling Identifies HSV-associated Inflammatory Macrophage Niches Linked to Oncolytic Virotherapy Response in Melanoma

Emma Wagner, Samuel Legg, Christopher J. Applebee…·Amanda Kirane

1 citation

humanspatial transcriptomics

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Cancer BiologybioRxivPreprintJul 30, 2025

AXL inhibition reprograms tumor-associated macrophages to restore immune checkpoint blockade efficacy in a polarization-context-dependent manner

Amanda Kirane, David Lee, Saurabh Sharma…·Emanual Michael Maverakis

DOI 10.1101/2025.07.30.667666

mousebulk RNA-seq

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Cancer BiologybioRxivPreprintMay 29, 2025

Functional Spatial Mapping of the Tumour Immune Microenvironment In Advanced Melanoma Patients

Emma Wagner, Samuel R.W. Legg, Christopher J. Applebee…·Banafshé Larijani

This study maps PD-1/PD-L1 functional interactions in melanoma tissues before and after ICB, showing spatial heterogeneity and persistent interactions post-treatment.

2 citations

humanspatial transcriptomics

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ImmunologybioRxivPreprintOct 6, 2024

Targeting DNA-PK is a highly conserved poxvirus innate immune evasion mechanism

Marisa Oliveira, Paul T. Manna, Damaris Ribeiro Rodrigues…·Brian J. Ferguson

This study shows that DNA-PK is a conserved DNA sensor in chickens that poxviruses evade by targeting with OPG020/OPG031 proteins, highlighting its role in innate immunity beyond mammals.

DOI 10.1101/2024.10.06.616852

chicken / avianexperimental assay

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