ImmunologybioRxivPreprint
Aromatic Microbial Metabolite Hippuric Acid Potentiates Pro-Inflammatory Responses in Macrophages through TLR-MyD88 Signaling and Lipid Remodeling
Gauri Mirji, Sajad Ahmad Bhat, Mohamed E. El Sayed…·Rahul Suresh Shinde
This study identifies hippuric acid as a microbial metabolite that enhances pro-inflammatory responses in macrophages via TLR-MyD88 signaling and lipid remodeling, with implications for infection and inflammation.
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