Qin Liu

This study shows that microglia-derived small extracellular vesicles promote monocyte expansion and recruitment in glioblastoma by activating MAPK signaling and inflammatory programs.

This study identifies TFAP2A as a driver of BRAF/MEK inhibitor resistance and immunosuppression, showing its disruption enhances antitumor immunity and overcomes drug resistance.

This study identifies CDC7 and POU2F1 as direct targets of EBNA1 in EBV+ epithelial cancers using VK1727 inhibition, revealing new therapeutic strategies.

The paper identifies the MYC-ATF4-ASS1 axis in melanoma that controls arginine synthesis and modulates immune responses, showing therapeutic potential with arginine depletors and BRAF/MEK inhibitors.

This study identifies UVRAG as a negative regulator of NOTCH1 by promoting K27-linked ubiquitination and lysosomal degradation, revealing a checkpoint to prevent excessive NOTCH signaling.

This study examines SIV dissemination in rhesus macaques after rectal infection, showing systemic infection occurs without local viral amplification at the entry site.

This study identifies hippuric acid as a microbial metabolite that enhances pro-inflammatory responses in macrophages via TLR-MyD88 signaling and lipid remodeling, with implications for infection and inflammation.